Fakhri appeared on America's Next Top Model Cycles 2 and 3 in 2004. She posed for the 2009 Kingfisher Swimsuit Calendar. In 2011, she made her feature film debut in the Bollywood film, Rockstar, alongside Ranbir Kapoor which was released on November 11, 2011. Fakhri has reportedly signed her second film, Khiladi 786, with Akshay Kumar.
Fakhri was born in Queens, New York to a Czech mother and a Pakistani father. Her parents divorced each other when she was barely six or seven years old. Fakhri is a U.S. citizen. When asked about her father's homeland, she revealed that she has never visited Pakistan. Her favourite hobbies include cooking, meditation and yoga.